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- Included with SigmaPlot
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Analyze
and plot ligand/receptor and dose response
data quickly and easily
Automatically fit radioligand and dose response
equations for multiple compounds with replicate
data. Select the type of study in the customized
dialog and specify the number of replicate
values to instantly plot and analyze your data.
All graphs and analysis appear as notebook
items to efficiently manage your work. [top] |
Select
from a wide range of models to determine
parameter values
Choose from ten built-in equations, create
a new equation or modify an existing equation
to analyze the number of binding sites, and
their affinity for various drugs. Fit one and
two site saturation equations to determine
the number of binding sites, Bmax, and the
ligand affinity, Kd. Fit competition and sigmoidal
dose-response equations to learn the affinity
of the receptor for the competing molecule,
EC50, or specify ligand concentration and Kd
to generate Ki, the equilibrium dissociation
constant .Automatically generate a report with
the equation fit results and the associated
error analysis. [top] |
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Save time
by plotting multiple compounds simultaneously
Automatically generate a plot of mean response
versus concentration and include the best-fit
lines for each compound. Modify your graph
as desired to present your results exactly
the way you want. Specify the fit range, minimum
and maximum x values, to customize your analysis.
Clearly distinguish different compounds with
symbols and legends. [top] |
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